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HTA & Modelling Science Lead

AstraZeneca -
Barcelona, Barcelona provincia

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Detalles del empleo

Jornada completa

Cualificaciones

Software estadístico
Economía
Microsoft Excel
SAS
R
Grado

Descripción completa del empleo

Posted date May. 11, 2026

Contract type Full time

Job ID R-252029

Why choose AstraZeneca Spain?

AstraZeneca Spain is a rising force in our global business. With headquarters in Madrid and our global hub in Barcelona, we’ve become an important international centre of excellence in the fight against critical disease. Boasting vibrant universities and business schools, the Barcelona ecosystem is a place where scientists can thrive. We attract a diverse workforce from across the globe, shining a beacon for innovation in a country that’s committed to clinical development.

We invite you to bring your talents to Barcelona where our respiratory medicine R&D and Global Marketing centre offers opportunities in R&D, IT, Commercial and HR. Or join us in Madrid and shape our growth in our BUs (Respiratory, Oncology & CVRM ), and a range of Corporate functions. Additionally, you can find sales roles throughout the country. Together, we’re contributing to a world-leading pipeline of therapeutics and delivering life-changing medicines to patients.

Who do we look for?

Calling all tech innovators, ownership takers, challenge seekers and proactive collaborators. At AstraZeneca Spain, breakthroughs born in the lab become transformative medicine for the world's most complex diseases. Alongside technical expertise, colleagues have the resilience, energy and collaborative mindset to change lanes, work with different teams and start projects from scratch.

Here, diverse minds and bold disruptors can meaningfully impact the future of healthcare using cutting-edge technology. Whether you join us in Madrid or Barcelona, you can make a tangible impact within a global biopharmaceutical company that invests in your future. Join a talented global team that's powering AstraZeneca to better serve patients every day.

Success Profile

Ready to make an impact in your career? If you're passionate, growth-orientated and a true team player, we'll help you succeed. Here are some of the skills and capabilities we look for.

Diverse collaborators

This is a speak-up culture that values collaboration. You’ll proactively bring your unique perspectives, experiences and skills to the table and seek the same from others. With our international team composition and the need for fast-paced collaboration, you’ll always be building new connections with colleagues.

Cutting-edge innovators

When you join us, you’ll be part of a team that embraces digital technology and data to transform the way we work and the work we do. Every day, you’ll help make history, empowered to ignite your creativity and build something enduring.

Resilient trailblazers

Here, the answers aren’t always available. So, you’ll need to bring a fearless, self-starter mindset to navigate uncharted territories. You’ll harness your ceaseless energy to discover and make the necessary connections with colleagues to shape the future and achieve maximum impact.

Agile movers

Seize ownership and excel with autonomy to enjoy the constant rush of ground-breaking discovery. Your ability to anticipate sudden shifts and adapt swiftly will prove critical as you make your mark in an environment that rewards initiative and resilience.

Responsibilities

Job ID R-252029 Date posted 05/11/2026

Introduction:

At AstraZeneca we are dedicated to redefining the future of healthcare by unlocking the power of what science can do for people, society and the planet. Working here means being bold, thinking big and working together to use the potential of science to address the unmet needs of patients around the world.

To deliver our medicines to patients we need to develop evidence for health technology assessment (HTA) bodies and payers around the world. This requires expertise in HTA science where we can translate data into evidence to support decision-making across the lifecycle of our medicines. In Europe, the start of the Joint Clinical Assessment (JCA) will require innovative solutions in demonstrating our comparative effectiveness through direct and indirect analyses, and consideration of how we pull through such evidence into economic value at the national level.

With our expanding oncology portfolio and increasing use of HTA around the globe, we are looking for a passionate and talented individual with experience and pragmatic expertise in health economic modelling to join our global oncology HTA and Modelling Science (HMS) team to support HTA strategy and submission work. Working collaboratively with our cross functional partners, you’ll contribute your expertise to develop, evaluate, and communicate patient and economic value, helping to secure patient access to our innovative medicines.

What we offer:

Impact: A role where your work directly influences HTA outcomes and patient access.

Development: A learning culture including technical, business acumen and leadership, with opportunities to shape methods and be recognized internally and externally for your expertise.

Inclusivity: An inclusive, supportive and respectful team culture, based in a new, state of the art office in the vibrant city of Barcelona.

Typical Accountabilities:

Contribute to development of strategic approach and delivery of health economic (HE) models for HTA submissions across the globe. This may include developing model specification documents, creating Excel (and/or R-based) models, report writing, training and/or dissemination, as well as supporting marketing teams in their HTA interactions.

Act as a primary point of contact for guidance, advice, and support on HE deliverables

Application of novel modelling methodologies, for example, surrogacy methods, survival and regression analyses.

Beyond HTA and market access, identify and apply HTA methods to support wider cross functional decision-making and goals (e.g. medical and commercial)

Provide leadership, input and support for the development of HMS tools, guidance documents, internal initiatives, as well as external publications

Contribute to quality assurance of the team’s work, projects led by external vendors, global standards, best practice, and metrics

Management of modelling projects undertaken by external vendors

Build partnerships and working relationships with cross-functional partners

We welcome candidates who may not meet every listed criterion, provided you bring the core skills and relevant experience for this role. If you’re motivated by improving patient access and have relevant skills, we encourage you to apply.

Key Skills/Experience:

Bachelors’ or post-graduate degree in economics, health economics, statistics/biostatistics, mathematics or equivalent quantitative degree with a statistical component

Prior experience (minimum 5 years) working in consultancy or industry in applying modelling expertise to support HTA submissions

Expert knowledge and experience in economic modelling and budget impact analysis, including hands-on model development in Excel

Understanding and application of statistical principles, methods, and procedures in the HTA setting, including the use of evidence synthesis, clinical trial analysis or analysis of other large datasets to support model development.

Experience in contributing to HTA submissions and responding to questions in at least one HTA market

Proven oral and written skills in communication of methods, results and data interpretation to different audiences

Strong interpersonal, organisational, and communication skills, with the ability to collaborate effectively with individuals from a variety of disciplines and backgrounds

Understanding of how HTA science can impact on wider market access and value communication

Ability to work both independently and as a team, and to take full accountability over projects

Desirable Skills/Experience:

Knowledge and experience across different oncology tumour types or disease stage settings

Direct hands-on experience in conducting indirect treatment comparisons and performing statistical analyses of clinical trial data for HTA, including but not limited to, patient reported outcomes and survival analyses.

Experience with R, SAS or similar statistical software packages

Knowledge of the changing HTA methods requirements globally and how to approach these.

Experience working with generative artificial intelligence (genAI) to support the development of health economic models and HTA deliverables

Key Stakeholders:

HTA and Modelling Science colleagues

Oncology Biometrics (statistics and programming)

Our wider Oncology Market Access and Pricing (OMAP) community, including payer evidence team

Marketing company / local affiliate HTA/HEOR related teams

Medical Affairs and medical evidence teams

Clinical outcomes assessment and patient cantered science teams

Clinical Development teams

Date Posted

04-ago-2026

Closing Date

31-ago-2026

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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Reasons to Join

Thomas Mathisen

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Sales Representative Oslo, Norway

Christine Recchio

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Sales Representative California, United States

Stephanie Ling

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

Sales Representative Petaling Jaya, Malaysia

What we offer

We're driven by our shared values of serving people, society and the planet. Our people make this possible, which is why we prioritise diversity, inclusivity, balance and sustainability. Discover what a career at AstraZeneca could mean for you.

An award-winning company

We're passionate about being a great place to work, and 84% of our employees would recommend us as an employer. We've been recognised as a Top Employer in Spain, an EFR Family Responsible Business, and we achieved third place in Forbes Spain's Top 50 Best Places to Work list.

Inclusive environment

Diversity and inclusion are embedded in everything we do, and our different views, experiences and strengths enrich our culture. There's no salary gap at AstraZeneca, and the number of female employees has increased by four per cent over the last three years. We've also made all positions fully accessible.

Work-life balance

Your wellbeing means a lot to us, and we're here to support you through all of life's ups and downs. That's why we offer an unpaid leave policy, annual leave, reduced-hours timetables and a host of benefits, including a retirement plan, long service award, and health and travel insurance.

Sustainability initiatives

We're committed to harnessing the power of science to become a more sustainable business. We've reduced our carbon footprint by over 9,000 kg of CO2 over the last two years, and we lead the European GoGreen Project, which aims to introduce environmentally friendly options in our fleet of corporate vehicles.

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