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Director of Clinical Pharmacology and Quantitative Pharmacology
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Medical Director, Global Patient Safety

AstraZeneca -
Barcelona, Barcelona provincia

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Detalles del empleo

Cualificaciones

Microsoft Powerpoint
Microsoft Word
Enfermería
Microsoft Excel
Optimización de la conversión
Farmacia
Habilidades de comunicación

Descripción completa del empleo

Location Barcelona, Catalonia, Spain Job ID R-245449 Date posted 01/07/2026

This is what you will do:

The Medical Director, Global Patient Safety (GPS) is accountable for executing the safety and risk management activities for one or more assigned clinical development projects or marketed products to enable the safe and effective use of Alexion’s products by patients and healthcare providers. The Medical Director will be responsible for safety activities for investigational products and/or marketed, including identification and evaluation of safety signals and risk management to drive decision-making on risk/benefit evaluation. The Medical Director GPS will be supervised by Global Safety Program Lead.

You will be responsible for:

Leading risk management evaluation and resolution for assigned products and projects. Accountability/responsible for the following:

Responsible for the overall scientific and clinical safety content for the assigned asset(s) or indications.

Responsible for the implementation and the high quality delivery of the Safety & Strategy Management Team (SSaMT) and Safety Surveillance Team for assigned asset(s).

Responsible for overall safety content for the product or indication(s) aligned to GPT strategy. Sets safety team goals aligned to TA and product strategy.

For the assigned asset(s), responsible for safety TPP, Safety Go/No Go criteria, safety communication/messaging and the guidelines for toxicity management of the asset

Responsible for safety contribution to study designs and study concept delivery within their assigned program

Chairing and/or directing the Safety Management Team for the assigned project(s) or product(s) ensuring a safety and risk/benefit driven agenda from inception to closure

Representing Alexion GPS at internal strategic and/or advisory/governance committees, other project/product team(s) or subteam(s) as a key cross functional member and subject matter expert, and/or act as an external technical resource at DSMB or Regulatory Authority meetings

Detecting, validating, and managing pre-and/or post-approval safety signals through to resolution

Evaluating aggregate safety data and providing contributions to core regulatory documents i.e. Periodic Safety Update Reports, Drug Safety Update Reports, Risk Management Plans, and other routine and non-routine safety and risk/benefit evaluations for internal or regulatory purposes as required

Identifying, initiating, and managing to completion, necessary updates to the IB, CCSI and/or local product information, Medication Guide, Patient Leaflet, and other labeling documentation as necessary

Overseeing safety sections of documents and safety interactions with Regulatory authorities. This may include: authorship of safety summaries to support changes to the PI/SmPC, significant contribution to MAAs and NDAs

Delivers analyses of clinical safety data in a balanced and statistically robust manner, to drive interpretations and develop novel proposals.

Serves as a source of scientific and clinical safety knowledge for the Product Team, in the analyses and interpretation of scientific and clinical safety data.

This job description is not exhaustive and may include other other job-related duties as assigned.

You will need to have:

MD or equivalent degree or a life sciences/pharmacy/nursing degree, and demonstrated Patient Safety and/or Clinical/ Drug Development experience

Sound problem solving skills including the ability to make decisions by developing innovative options and/or multiple solutions to highly complex problems

The ability to manage multiple overlapping complex tasks to conclusion, sometimes to tight timelines, for several projects and sub-projects, including oversight of others working on those projects

Knowledge and understanding of GPS deliverables, standards and processes

Knowledge and understanding of US and EU safety regulations pre- and post- marketing

The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

We would prefer for you to have:

2-3 years relevant safety and risk management experience in the pharmaceutical, biotech or CRO industry

Rare, Ultra-Rare or Orphan Disease Area experience

Strong verbal and written communication skills including making recommended courses of action to management and/or senior leaders that impact the discipline, department or line, and influences their decisions

Excellent, independent judgment based on knowledge and expertise

Strong personal time-management and project-management skills

Mastery of Microsoft Word, PowerPoint and Excel

Date Posted

02-Jul-2026

Closing Date

30-Jul-2026

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact [email protected]. Alexion participates in E-Verify.

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